Resveratrol inhibits Cdk5 activity through regulation of p35 expression

• 主要な著者: Kulkarni Ashok B (著者), Iadarola Michael J (著者), Keller Jason (著者), Terse Anita (著者), Utreras Elias (著者)
• フォーマット: 図書
• 出版事項: SAGE Publishing, 2011-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>We have previously reported that cyclin-dependent kinase 5 (Cdk5) participates in the regulation of nociceptive signaling. Through activation of the ERK1/2 pathway, Tumor Necrosis Factor-α (TNF-α) induces expression of Egr-1. This re...