New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors

• Main Authors: Elena Gabriele (Author), Dario Brambilla (Author), Chiara Ricci (Author), Luca Regazzoni (Author), Kyoko Taguchi (Author), Nicola Ferri (Author), Akira Asai (Author), Anna Sparatore (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A set of new sulfurated drug hybrids, mainly derived from caffeic and ferulic acids and rosmaricine, has been synthesized and their ability to inhibit both STAT3 and NF-κB transcription factors have been evaluated. Results showed that most of the new hybrid compounds were able to strongly and select...