Towards Improved Management of Tuberculous Bloodstream Infections: Pharmacokinetic Considerations with Suggestions for Better Treatment Outcomes

• Main Authors: Charles Okot Odongo (Author), Lydia Nakiyingi (Author), Clovis Gatete Nkeramihigo (Author), Daniel Seifu (Author), Kuteesa Ronald Bisaso (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Mycobacterium tuberculosis</i> is the leading cause of sepsis among HIV-infected adults, yet effective treatment remains a challenge. Efficacy of antituberculous drugs is optimized by high Area Under Curve to Minimum Inhibitory Concentration (AUC/MIC) ratios, suggesting that both the...