NHERF1/EBP50 as a Target for Modulation of MRP Function in HepG2 Cells

• Main Authors: Atsushi Kawase (Author), Miho Hirosoko (Author), Yuka Sugihara (Author), Yunosuke Koyama (Author), Ayaka Fukae (Author), Hiroaki Shimada (Author), Masahiro Iwaki (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As increased expression and activities of efflux transporters (ETs) often cause drug resistance in cancers, we tried modulating ET activity in cancer cells, using scaffold proteins such as ezrin/radixin/moesin (ERM) proteins, and Na⁺/H⁺ exchanger regulat...