Destabilization of spindle assembly checkpoint causes aneuploidy during meiosis II in murine post-ovulatory aged oocytes

Mammalian oocyte quality degrades over time after ovulation in vitro, which can cause fatal defects such as chromosomal aneuploidy. As various oocyte manipulations employed in assisted reproductive technology are time consuming, post-ovulatory aging is a serious problem to overcome in reproductive m...

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Bibliographic Details
Main Authors: Gaku SHIMOI (Author), Masaru TOMITA (Author), Marino KATAOKA (Author), Yuichi KAMEYAMA (Author)
Format: Book
Published: The Society for Reproduction and Development, 2018-11-01T00:00:00Z.
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