Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis

Background: Innate immune response components such as toll-like receptors (TLRs) and NLRP3-inflammasome act in concert to increase IL-1α/β secretion by synovial macrophages. Previous results suggest that IL-1α/β could be an important mediator involved in the pathogenesis of osteoarthritis (OA).Objec...

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Main Authors: Sonia Nasi (Author), Hang-Korng Ea (Author), Alexander So (Author), Nathalie Busso (Author)
Format: Book
Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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