The spectrum of clinical sequelae associated with alpha-1 antitrypsin deficiency

Alpha-1 antitrypsin (AAT) deficiency (AATD) is an autosomal co-dominant condition that predisposes to the development of lung disease, primarily emphysema. Emphysema results from the breakdown of lung matrix elastin by proteases, including neutrophil elastase, a protease normally inhibited by AAT. A...

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Main Authors: Vickram Tejwani (Author), James K. Stoller (Author)
Format: Book
Published: SAGE Publishing, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available