Stimulation of Cultured H9 Human Embryonic Stem Cells with Thyroid Stimulating Hormone Does Not Lead to Formation of Thyroid-Like Cells

• Main Authors: Mykola I. Onyshchenko (Author), Igor G. Panyutin (Author), Irina V. Panyutin (Author), Ronald D. Neumann (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2012-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The sodium-iodine symporter (NIS) is expressed on the cell membrane of many thyroid cancer cells, and is responsible for the radioactive iodine accumulation. However, treatment of anaplastic thyroid cancer is ineffective due to the low expression of NIS on cell membranes of these tumor cells. Human...