CLINICAL EFFECTIVENESS OF OSMOTIC LAXATIVE DRUGS IN EARLY POSTOPERATIVE PERIOD IN CHILDREN WITH CHRONIC COLON STASIS

• Main Authors: P.V. Ivanov (Author), I.V. Kirgizov (Author), I.A. Shishkin (Author), K.N. Baranov (Author), A.A. Mikhailovskiy (Author)
• Format: Book
• Published: "Paediatrician" Publishers LLC, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1682-5527; 1682-5535
• Keywords: Pediatrics; RJ1-570
• Source: Вопросы современной педиатрии, Vol 9, Iss 1, Pp 122-125 (2010)

<p><em>The clinical effectiveness of osmotic laxative drugs based on lactulose in restoration of gastrointestinal tract function in early postoperative period after transanal interventions and laparoscopic operations in 53 children 2-17 years old was studied. All patients had non-functional (cologenic and proctogenic) constipation. Patients underwent full-thickness laparoscopic or transanal biopsy due to suspicion of gastrointestinal malformation presence. Children from base group (n = 28) used lactulose (Duphalac) from the second day of postoperative period (dose complied with the age) once daily, in the morning. The control group (n = 25) received subcutaneous or intramuscular proserinum for the stimulation of peristalsis. Blood tests with serum potassium control were performed on 2nd and 4^t^h day. The study showed clinical effectiveness of lactulose in treatment of postoperational hypotonic constipation in children with colon malformations. </em><strong><em></em></strong></p><p><strong><em>Key words: children, gastrointestinal malformations, postoperative period, chronic constipation, lactulose.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii - </em></em></em>Current Pediatrics. 2010;9(1):122-125)</em></span></p>