Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway

• Main Authors: Hongbo Wang (Author), Xiaojuan Bi (Author), Rongyao Zhang (Author), Hailong Yuan (Author), Jianli Xu (Author), Kaile Zhang (Author), Songqing Qi (Author), Xue Zhang (Author), Ming Jiang (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Poor graft function (PGF) is a life-threatening complication following hematopoietic stem cell transplantation (HSCT). Current therapies, such as CD34+ cell infusion, have shown limited effectiveness. Conversely, mesenchymal stem cells (MSCs) show potential in addressing PGF. Adipose-der...