VSELs and OSCs together sustain oogenesis in adult ovaries and their dysfunction results in age-related senescence, PCOS, POI and cancer

• Main Authors: Deepa Bhartiya (Author), Diksha Sharma (Author)
• פורמט: ספר
• יצא לאור: BMC, 2023-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Multiple studies using single-cell RNA sequencing (scRNAseq) have failed to detect stem cells in adult ovaries. We have maintained that two populations of ovarian stem cells including pluripotent, very small embryonic-like stem cells (VSELs) and tissue-committed 'progenitors' term...