Quantitative determination of imatinib stability under various stress conditions

• Main Authors: Khalid Mohammed Alkharfy (Author), Rao Muzaffer Ali Khan (Author), Majed Al-Asmari (Author), Baderelddin Hashim Alhadeyah (Author), Ajaz Ahmad (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: A simple, rapid, reverse phase and stability-indicating high-performance liquid chromatography (HPLC) method for the estimation of imatinib in solution and in plasma under forced degradation conditions was developed. Materials and Methods: The method employed isocratic elution using a Wat...