Zika virus disrupts gene expression in human myoblasts and myotubes: Relationship with susceptibility to infection.

• Main Authors: Ingo Riederer (Author), Daniella Arêas Mendes- (Author), Guilherme Cordenonsi da Fonseca (Author), Mariela Natacha González (Author), Otavio Brustolini (Author), Cássia Rocha (Author), Guilherme Loss (Author), Joseane Biso de Carvalho (Author), Mariane Talon Menezes (Author), Lidiane Menezes Souza Raphael (Author), Alexandra Gerber (Author), Myrna Cristina Bonaldo (Author), Gillian Butler-Browne (Author), Vincent Mouly (Author), Vinicius Cotta- (Author), Wilson Savino (Author), Ana Tereza Ribeiro de Vasconcelos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tropism of Zika virus (ZIKV) has been described in the nervous system, blood, placenta, thymus, and skeletal muscle. We investigated the mechanisms of skeletal muscle susceptibility to ZIKV using an in vitro model of human skeletal muscle myogenesis, in which myoblasts differentiate into myotube...