Modulation of endothelial cell migration by ER stress and insulin resistance: a role during maternal obesity?

• Hoofdauteurs: Pablo José Sáez (Auteur), Roberto eVillalobos-Labra (Auteur), Francisco eWestermeier (Auteur), Luis eSobrevia (Auteur), Marcelo eFarías-Jofré (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Adverse microenvironmental stimuli can trigger the endoplasmic reticulum (ER) stress pathway, which initiates the unfolded protein response (UPR), to restore protein-folding homeostasis. Several studies show induction of ER stress during obesity. Chronic UPR has been linked to different mechanisms o...