Modulation of endothelial cell migration by ER stress and insulin resistance: a role during maternal obesity?

• Main Authors: Pablo José Sáez (Author), Roberto eVillalobos-Labra (Author), Francisco eWestermeier (Author), Luis eSobrevia (Author), Marcelo eFarías-Jofré (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adverse microenvironmental stimuli can trigger the endoplasmic reticulum (ER) stress pathway, which initiates the unfolded protein response (UPR), to restore protein-folding homeostasis. Several studies show induction of ER stress during obesity. Chronic UPR has been linked to different mechanisms o...