Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor

• Main Authors: Ophelia Yin (Author), Hamim Zahir (Author), Jonathan French (Author), Daniel Polhamus (Author), Xiaoning Wang (Author), Michiel van deSande (Author), William D. Tap (Author), Hans Gelderblom (Author), Andrew J. Wagner (Author), John H. Healey (Author), Jonathan Greenberg (Author), Dale Shuster (Author), Silvia Stacchiotti (Author)
• Format: Book
• Published: Wiley, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This analysis was conducted to assess exposure-response relationships for efficacy and safety of pexidartinib in patients with tenosynovial giant cell tumor. Efficacy was assessed categorically by overall response rate (ORR) with Response Evaluation Criteria in Solid Tumors version 1.1 and...