9-PAHSA displays a weak anti-inflammatory potential mediated by specific antagonism of chemokine G protein-coupled receptors

• Main Authors: Paulus Wohlfart (Author), Mounir Chehtane (Author), Ernesto Luna (Author), Riyaz Mehta (Author), Marcus Korn (Author), Anish Konkar (Author), Uwe Schwahn (Author), Stefan Petry (Author), Norbert Tennagels (Author), Maximilian Bielohuby (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: 9-PAHSA belongs to a class of endogenous mammalian bioactive lipids, fatty acid esters of hydroxy fatty acids (FAHFA), that are present in circulation at nanomolar concentrations in mice and humans. Published preclinical data suggest beneficial effects of 9-PAHSA treatment on glucose m...