Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease

Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologic mediator NO. sGC stimulators are small...

Full description

Saved in:
Bibliographic Details
Main Authors: Daniel P. Zimmer (Author), Courtney M. Shea (Author), Jenny V. Tobin (Author), Boris Tchernychev (Author), Peter Germano (Author), Kristie Sykes (Author), Ali R. Banijamali (Author), Sarah Jacobson (Author), Sylvie G. Bernier (Author), Renee Sarno (Author), Andrew Carvalho (Author), Yueh-tyng Chien (Author), Regina Graul (Author), Emmanuel S. Buys (Author), Juli E. Jones (Author), James D. Wakefield (Author), Gavrielle M. Price (Author), Jennifer G. Chickering (Author), G. Todd Milne (Author), Mark G. Currie (Author), Jaime L. Masferrer (Author)
Format: Book
Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available