Do small effects matter more in vulnerable populations? an investigation using Environmental influences on Child Health Outcomes (ECHO) cohorts

• Main Authors: Janet L. Peacock (Author), Susana Diaz Coto (Author), Judy R. Rees (Author), Odile Sauzet (Author), Elizabeth T. Jensen (Author), Raina Fichorova (Author), Anne L. Dunlop (Author), Nigel Paneth (Author), Amy Padula (Author), Tracey Woodruff (Author), Rachel Morello-Frosch (Author), Jessica Trowbridge (Author), Dana Goin (Author), Luis E. Maldonado (Author), Zhongzheng Niu (Author), Akhgar Ghassabian (Author), Leonardo Transande (Author), Assiamira Ferrara (Author), Lisa A. Croen (Author), Stacey Alexeeff (Author), Carrie Breton (Author), Augusto Litonjua (Author), Thomas G. O'Connor (Author), Kristen Lyall (Author), Heather Volk (Author), Akram Alshawabkeh (Author), Justin Manjourides (Author), Carlos A. Camargo (Author), Dana Dabelea (Author), Christine W. Hockett (Author), Casper G. Bendixsen (Author), Irva Hertz-Picciotto (Author), Rebecca J. Schmidt (Author), Alison E. Hipwell (Author), Kate Keenan (Author), Catherine Karr (Author), Kaja Z. LeWinn (Author), Barry Lester (Author), Marie Camerota (Author), Jody Ganiban (Author), Cynthia McEvoy (Author), Michael R. Elliott (Author), Sheela Sathyanarayana (Author), Nan Ji (Author), Joseph M. Braun (Author), Margaret R. Karagas (Author), on behalf of Program Collaborators for Environmental influences on Child Health Outcomes (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A major challenge in epidemiology is knowing when an exposure effect is large enough to be clinically important, in particular how to interpret a difference in mean outcome in unexposed/exposed groups. Where it can be calculated, the proportion/percentage beyond a suitable cut-po...