Silibinin Protects Against Isoproterenol-Induced Rat Cardiac Myocyte Injury Through Mitochondrial Pathway After Up-regulation of SIRT1

• Main Authors: Bei Zhou (Author), Li-Jun Wu (Author), Lin-Hao Li (Author), Shin-ichi Tashiro (Author), Satoshi Onodera (Author), Fumiaki Uchiumi (Author), Takashi Ikejima (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Terminally differentiated adult injured cardiac myocytes have been used for various animal models of heart failure. It has recently been shown that isoproterenol induces injury in rat neonatal cardiac myocytes via a β-adrenergic pathway, suggesting that it might be one of the factors involved in myo...