Pharmacokinetics and tissue distribution of LN002, a new compound alternative oxidase inhibitor against Cryptosporidium in rats

• Main Authors: Minglang Ma (Author), Yongxiang Zhang (Author), Yanjun Fang (Author), Yixing Lu (Author), Huiguo Huang (Author), Zhenling Zeng (Author), Dongping Zeng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cryptosporidiosis is considered a crucial zoonotic disease caused by widely distributing parasitic protozoa called Cryptosporidium spp. Nitazoxanide is the only FDA-approved drug but is only effective with a good immune response of the host. In addressing this unmet medical need, we previously ident...