Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/β-catenin signaling pathway

• Main Authors: Minguen Yoon (Author), Heejene Kim (Author), Heewon Shin (Author), HeeYang Lee (Author), Min-Jeong Kang (Author), Sung-Hye Park (Author), Gyoonhee Han (Author), YoungSoo Kim (Author), Kang-Yell Choi (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is the most prevalent type of dementia and is characterized by cognitive deficits and accumulation of pathological plaques. Owing to the complexity of AD development, paradigms for AD research and drug discovery have shifted to target factors that mediate multiple patho...