Exploring disease-specific methylated CpGs in human male genital abnormalities by using methylated-site display-amplified fragment length polymorphism (MSD-AFLP)

• Main Authors: Toshiki AIBA (Author), Toshiyuki SAITO (Author), Akiko HAYASHI (Author), Shinji SATO (Author), Harunobu YUNOKAWA (Author), Maki FUKAMI (Author), Yutaro HAYASHI (Author), Kentaro MIZUNO (Author), Yuichi SATO (Author), Yoshiyuki KOJIMA (Author), Seiichiroh OHSAKO (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The incidence of male reproductive system disorders, especially hypospadias, has been increasing in developed countries since the latter half of the 20th century. Endocrine-disrupting chemicals from the environment are considered to be involved in hypospadias onset through epigenetic alterations. Th...