Machine Learning for Exposure-Response Analysis: Methodological Considerations and Confirmation of Their Importance via Computational Experimentations

Exposure-response (E-R) is a key aspect of pharmacometrics analysis that supports drug dose selection. Currently, there is a lack of understanding of the technical considerations necessary for drawing unbiased estimates from data. Due to recent advances in machine learning (ML) explainability method...

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Main Authors: Rashed Harun (Author), Eric Yang (Author), Nastya Kassir (Author), Wenhui Zhang (Author), James Lu (Author)
Format: Book
Published: MDPI AG, 2023-04-01T00:00:00Z.
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