Targeting human MutT homolog 1 (MTH1) for cancer eradication: current progress and perspectives
Since accelerated metabolism produces much higher levels of reactive oxygen species (ROS) in cancer cells compared to ROS levels found in normal cells, human MutT homolog 1 (MTH1), which sanitizes oxidized nucleotide pools, was recently demonstrated to be crucial for the survival of cancer cells, bu...
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Elsevier,
2020-12-01T00:00:00Z.
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