Lipid-nanoparticle-enabled nucleic acid therapeutics for liver disorders

• Main Authors: Porkizhi Arjunan (Author), Durga Kathirvelu (Author), Gokulnath Mahalingam (Author), Ashish Kumar Goel (Author), Uday George Zacharaiah (Author), Alok Srivastava (Author), Srujan Marepally (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inherited genetic disorders of the liver pose a significant public health burden. Liver transplantation is often limited by the availability of donor livers and the exorbitant costs of immunosuppressive therapy. To overcome these limitations, nucleic acid therapy provides a hopeful alternative that...