Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160
Laminin-111 protein complex links the extracellular matrix to integrin α7β1 in sarcolemma, thus replacing in dystrophic muscles links normally insured by the dystrophin complex. Laminin-111 injection in mdx mouse stabilized sarcolemma, restored serum creatine kinase to wild-type levels, and protecte...
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| Materiálatiipa: | Girji |
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Elsevier,
2017-03-01T00:00:00Z.
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