Poria cocos polysaccharides exert prebiotic function to attenuate the adverse effects and improve the therapeutic outcome of 5-FU in Apc Min/+ mice

• Main Authors: Lin Yin (Author), Guoxin Huang (Author), Imran Khan (Author), Lu Su (Author), Wenrui Xia (Author), Betty Yuen Kwan Law (Author), Vincent Kam Wai Wong (Author), Qiang Wu (Author), Jingyi Wang (Author), Wai Kit Leong (Author), W. L. Wendy Hsiao (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background As a first-line chemotherapeutic agent, 5-fluorouracil (5-FU) exhibits many side effects, weakening its efficacy in cancer treatment. In this study, we hypothesize that Poria cocos polysaccharides (PCP), a traditional Chinese herbal medicine with various bioactivities and prebiot...