Chelerythrine chloride from Macleaya cordata induces growth inhibition and apoptosis in human gastric cancer BGC-823 cells

• Auteurs principaux: Zhengfu Zhang (Auteur), Ying Guo (Auteur), Lingwei Zhang (Auteur), Jianbin Zhang (Auteur), Xionghui Wei (Auteur)
• Format: Livre
• Publié: Elsevier, 2012-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

This study aimed to investigate the ability of chelerythrine chloride (CHE), the main active ingredient of Macleaya cordata, to induce apoptosis in human gastric cancer BGC-823 cells. The results demonstrate that CHE inhibits cell proliferation in a time- and dose-dependent manner with accompanying...