Biopharmaceutical profiling of anti-infective sanggenons from Morus alba root bark for inhalation administration

• Main Authors: Jacqueline Schwarzinger (Author), Sigrid Adelsberger (Author), Karin Ortmayr (Author), Sarah Luise Stellnberger (Author), Ammar Tahir (Author), Gabriela Hädrich (Author), Verena Pichler (Author), Judith M. Rollinger (Author), Ulrike Grienke (Author), Lea Ann Dailey (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mulberry Diels-Alder-type adducts (MDAAs), isolated from Morus alba root bark, exhibit dual activity against viral and bacterial pathogens but show sobering efficacy following oral administration. Inhalation administration may overcome issues with oral bioavailability and improve efficacy for the tr...