Analysis of the Association Between Polymorphisms within PAI-1 and ACE genes and Ischemic Stroke Outcome After rt-PA Therapy

• Main Authors: Marija Dušanović Pjević (Author), Ljiljana Beslac Bumbaširevic (Author), Ljubica Vojvodic (Author), Milka Grk (Author), Nela Maksimović (Author), Tatjana Damnjanović (Author), Ivana Novaković (Author), Katarina Kačar (Author), Milica Pesic (Author), Dijana Perovic (Author), Milan Savic (Author), Veljko Maksic (Author), Jelena Trickovic (Author), Biljana Jekic (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Treatment of Ischemic stroke (IS) in acute phase is based on the use of thrombolytic rt-PA therapy. We aimed to determine whether different alleles and genotypes of I/D ACE gene and 4G/5G PAI-1 gene polymorphisms may influence outcome of rt-PA therapy in patients with IS and the occurrence...