Mucoadhesive microemulsion of ibuprofen: design and evaluation for brain targeting efficiency through intranasal route

• Main Authors: Surjyanarayan Mandal (Author), Snigdha Das Mandal (Author), Krishna Chuttani (Author), Bharat Bhushan Subudhi (Author)
• Format: Book
• Published: Universidade de São Paulo, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed at designing mucoadhesive microemulsion gel to enhance the brain uptake of Ibuprofen through intranasal route. Ibuprofen loaded mucoadhesive microemulsion (MMEI) was developed by incorporating polycarbophil as mucoadhesive polymer into Capmul MCM based optimal microemulsion (MEI) an...