IL20Rb aggravates pulmonary fibrosis through enhancing bone marrow derived profibrotic macrophage activation

• Main Authors: Jingyan Zhu (Author), Qiuyan Jiang (Author), Shaoyan Gao (Author), Qin Xia (Author), Huizhe Zhang (Author), Bowen Liu (Author), Ruixi Zhao (Author), Haixia Jiang (Author), Xiaohe Li (Author), Aiguo Xu (Author), Honggang Zhou (Author), Zuojun Xu (Author), Cheng Yang (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is one of the most fatal chronic interstitial lung diseases with unknown pathogenesis, current treatments cannot truly reverse the progression of the disease. Pulmonary macrophages, especially bone marrow derived pro-fibrotic macrophages, secrete multiple kinds of...