DESI-TQ-MS imaging for ex vivo brain biodistribution assessment: evaluation of LBT-999, a ligand of the dopamine transporter (DAT)

DESI-TQ-MS imaging for ex vivo brain biodistribution assessment: evaluation of LBT-999, a ligand of the dopamine transporter (DAT)

Abstract Background Selection of the most promising radiotracer candidates for radiolabeling is a difficult step in the development of radiotracer pharmaceuticals, especially for the brain. Mass spectrometry (MS) is an alternative to study ex vivo the characteristics of candidates, but most MS studi...

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Main Authors: Laurent Galineau (Author), Emmanuelle Claude (Author), Zuhal Gulhan (Author), Sylvie Bodard (Author), Sophie Sérrière (Author), Camille Dupuy (Author), Jérémy Monteiro (Author), Adeline Oury (Author), Priscila Bertevello (Author), Gabrielle Chicheri (Author), Johnny Vercouillie (Author), Lydie Nadal-Desbarats (Author), Sylvie Chalon (Author), Antoine Lefèvre (Author), Patrick Emond (Author)
Format: Book
Published: SpringerOpen, 2024-08-01T00:00:00Z.
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