Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

• Main Authors: Mingming Zhang (Author), Shan Gao (Author), Dongjuan Yang (Author), Yan Fang (Author), Xiaojie Lin (Author), Xuechao Jin (Author), Yuli Liu (Author), Xiu Liu (Author), Kexin Su (Author), Kai Shi (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the expanded endothelial space and penetrated the dense stroma of tumor microenvironment to tumor cells. As long as p...