In silico identification and modification of T cell epitopes in pertussis antigens associated with tolerance

• Main Authors: Corine Kruiswijk (Author), Guilhem Richard (Author), Merijn L.M. Salverda (Author), Pooja Hindocha (Author), William D. Martin (Author), Anne S. De Groot (Author), Elly Van Riet (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The resurgence of whooping cough since the introduction of acellular (protein) vaccines has led to a renewed interest in the development of improved pertussis vaccines; Outer Membrane Vesicles (OMVs) carrying pertussis antigens have emerged as viable candidates. An in silico immunogenicity screen wa...