In silico identification and modification of T cell epitopes in pertussis antigens associated with tolerance

• Auteurs principaux: Corine Kruiswijk (Auteur), Guilhem Richard (Auteur), Merijn L.M. Salverda (Auteur), Pooja Hindocha (Auteur), William D. Martin (Auteur), Anne S. De Groot (Auteur), Elly Van Riet (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The resurgence of whooping cough since the introduction of acellular (protein) vaccines has led to a renewed interest in the development of improved pertussis vaccines; Outer Membrane Vesicles (OMVs) carrying pertussis antigens have emerged as viable candidates. An in silico immunogenicity screen wa...