Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

<p>Abstract</p> <p>Background</p> <p>Tetra-O-methyl nordihydroguaiaretic acid, also known as terameprocol (TMP), is a naturally occurring phenolic compound found in the resin of the creosote bush. We have shown previously that TMP will suppress production of certain inf...

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Main Authors: Scholle Frank (Author), Wilson Jason R (Author), Sikes Michael L (Author), Oyegunwa Akinbolade O (Author), Laster Scott M (Author)
Format: Book
Published: BMC, 2010-12-01T00:00:00Z.
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