In vitro evaluation suggests fenfluramine and norfenfluramine are unlikely to act as perpetrators of drug interactions

• 主要な著者: Parthena Martin (著者), Maciej Czerwiński (著者), Pallavi B. Limaye (著者), Brian W. Ogilvie (著者), Steven Smith (著者), Brooks Boyd (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Studies support the safety and efficacy of fenfluramine (FFA) as an antiseizure medication (ASM) in Dravet syndrome, Lennox‐Gastaut syndrome, or CDKL5 deficiency disorder, all pharmacoresistant developmental and epileptic encephalopathies. However, drug-drug interactions with FFA in multi‐A...