Hydrogen sulfide inhibits skeletal muscle ageing by up‐regulating autophagy through promoting deubiquitination of adenosine 5'‐monophosphate (AMP)‐activated protein kinase α1 via ubiquitin specific peptidase 5

• Main Authors: Jia‐He Yang (Author), Jun Gao (Author), Ya‐Qi E (Author), Li‐Jie Jiao (Author), Ren Wu (Author), Qiu‐Yi Yan (Author), Zi‐Yi Wei (Author), Guo‐Liang Yan (Author), Jin‐Long Liang (Author), Hong‐Zhu Li (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hydrogen sulfide (H2S), the third gasotransmitter discovered, regulates a variety of physiological functions. Whether H2S alleviates skeletal muscle ageing by regulating autophagy has not been reported. Methods Mice were administered 150 mg/kg/day of D‐galactose (D‐gal), and C2C1...