ARumenamides: A novel class of potential antiarrhythmic compounds
Background: Most therapeutics targeting cardiac voltage-gated sodium channels (Nav1.5) attenuate the sodium current (INa) conducted through the pore of the protein. Whereas these drugs may be beneficial for disease states associated with gain-of-function (GoF) in Nav1.5, few attempts have been made...
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Frontiers Media S.A.,
2022-09-01T00:00:00Z.
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