ARumenamides: A novel class of potential antiarrhythmic compounds

Background: Most therapeutics targeting cardiac voltage-gated sodium channels (Nav1.5) attenuate the sodium current (INa) conducted through the pore of the protein. Whereas these drugs may be beneficial for disease states associated with gain-of-function (GoF) in Nav1.5, few attempts have been made...

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Principais autores: Mena Abdelsayed (Autor), Dana Page (Autor), Peter C. Ruben (Autor)
Formato: Livro
Publicado em: Frontiers Media S.A., 2022-09-01T00:00:00Z.
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