Pharmacological Interaction With the Sigma1 (σ1)-Receptor in the Acute Behavioral Effects of Antidepressants
Selective agonists of the sigma-1 (σ1) ligand-operated chaperone protein, like igmesine or PRE-084, are antidepressants in preclinical depression models. σ1-Protein activation may contribute to the antidepressant efficacy of drugs known to act as selective serotonin-reuptake inhibitors (SSRI) or nor...
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Format: | Book |
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Elsevier,
2011-01-01T00:00:00Z.
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A1234.567 |
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