Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain

• Asıl Yazarlar: Andrea Maddalena (Yazar), Julia Tereshchenko (Yazar), Mathias Bähr (Yazar), Sebastian Kügler (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2013-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Gene therapy, in its current configuration, is irreversible and does not allow control over transgene expression in case of side effects. Only few regulated vector systems are available, and none of these has reached clinical applicability yet. The mifepristone (Mfp)-regulated Gene Switch (GS) syste...