Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes

• Main Authors: J. R. Thiele (Author), J. Zeller (Author), H. Bannasch (Author), G. B. Stark (Author), K. Peter (Author), S. U. Eisenhardt (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

C-reactive protein (CRP) is a pentraxin that has long been employed as a marker of inflammation in clinical practice. Recent findings brought up the idea of CRP to be not only a systemic marker but also a mediator of inflammation. New studies focused on structural changes of the plasma protein, reve...