Angiotensin 1-7 and losartan worsen the cisplatin induced nephrotoxicity in female rats

• Main Authors: Sayyedehnikta Kasaei (Author), Zahra Pezeshki (Author), Farzaneh Karimi (Author), Zahra Lak (Author), Samira Choopani (Author), Ardeshir Talebi (Author), Mehdi Nematbakhsh (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Cisplatin (CP) is an anti-cancer drug with the most common side effects of nephrotoxicity. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist and angiotensin 1-7 (Ang1-7) protects the kidney against CP administration in males Moreover, the activity of the renin angiotensin s...