An RGD-Conjugated Prodrug Nanoparticle with Blood-Brain-Barrier Penetrability for Neuroprotection Against Cerebral Ischemia-Reperfusion Injury

• Autori principali: Ayijiang Taledaohan (Autore), Maer Maer Tuohan (Autore), Renbo Jia (Autore), Kai Wang (Autore), Liujia Chan (Autore), Yijiang Jia (Autore), Feng Wang (Autore), Yuji Wang (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2024-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Cerebral ischemia-reperfusion injury significantly contributes to global morbidity and mortality. Loganin is a natural product with various neuroprotective effects; however, it lacks targeted specificity for particular cells or receptors, which may result in reduced therapeutic efficacy and an incre...