Development of Lipomer Nanoparticles for the Enhancement of <i>Drug</i> Release, Anti-Microbial Activity and Bioavailability of Delafloxacin

• Main Authors: Md. Khalid Anwer (Author), Muzaffar Iqbal (Author), Magdy M. Muharram (Author), Muqtader Mohammad (Author), Essam Ezzeldin (Author), Mohammed F. Aldawsari (Author), Ahmed Alalaiwe (Author), Faisal Imam (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Delafloxacin (DFL) is a novel potent and broad-spectrum fluoroquinolone group of antibiotics effective against both Gram-positive and negative aerobic and anaerobic bacteria. In this study, DFL-loaded stearic acid (lipid) chitosan (polymer) hybrid nanoparticles (L-P-NPs) have been developed by singl...