Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs

• Main Authors: Bianca L. Artiaga (Author), Igor Morozov (Author), Russell Ransburgh (Author), Taeyong Kwon (Author), Velmurugan Balaraman (Author), Sabarish V. Indran (Author), Darling Melany De Carvalho Madrid (Author), Weihong Gu (Author), Jamie Henningson (Author), Wenjun Ma (Author), Jürgen A. Richt (Author), John P. Driver (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Natural killer T (NKT) cells activated with the glycolipid ligand α-galactosylceramide (α-GalCer) stimulate a wide variety of immune cells that enhance vaccine-mediated immune responses. Several studies have used this approach to adjuvant inactivated and subunit influenza A virus (IAV) vacc...