Protection by ozone preconditioning is mediated by the antioxidant system in cisplatin-induced nephrotoxicity in rats

• Main Authors: Aluet Borrego (Author), Zullyt B. Zamora (Author), Ricardo González (Author), Cheyla Romay (Author), Silvia Menéndez (Author), Frank Hernández (Author), Teresita Montero (Author), Enys Rojas (Author)
• Format: Book
• Published: Hindawi Limited, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Acute renal failure is a dose-limiting factor of cisplatin chemotherapy. Here, we show the protective effect of ozone oxidative preconditioning against cisplatin-induced renal dysfunction in rats. Ozone oxidative preconditioning is a prophylactic approach, which favors the antioxidant-pr...