NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes

• Main Authors: Shiwei Wang (Author), Xuan Wu (Author), Mengmeng Zhang (Author), Siyu Chang (Author), Yajun Guo (Author), Shuang Song (Author), Shizhen Dai (Author), Keliang Wu (Author), Shenming Zeng (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Neuroepithelial transforming gene 1 (NET1) is a RhoA subfamily guanine nucleotide exchange factor that governs a wide array of biological processes. However, its roles in meiotic oocyte remain unclear. We herein demonstrated that the NET1-HACE1-RAC1 pathway mediates meiotic defec...