Pancreatic β-cell protective effect of novel GABA derivatives in rats with type 2 diabetes

• Main Authors: Ivan N. Tyurenkov (Author), Dmitry A. Bakulin (Author), Yulia I. Velikorodnaya (Author), Alexander V. Borisov (Author), Elizaveta E. Abrosimova (Author), Alexey V. Smirnov (Author), Grigoriy L. Snigur (Author), Svyatoslav S. Surin (Author), Daria A. Kavalerova (Author), Olga S. Vasilyeva (Author)
• Format: Book
• Published: Belgorod National Research University, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Gamma-aminobutyric acid (GABA) and GABAergic compounds emerged as potential therapeutic agents for diabetes mellitus and its complications. GABA acts as an inhibitory neurotransmitter in the central nervous system and as an extracellular signaling molecule in pancreatic islets, exertin...